NMN Stabilized Form 250mg Serving Nicotinamide Mononucleotide Direct NAD+ Supplement More Stable Than Riboside Works Best When Paired with Resveratrol

$93.99

Availability: 250 in stock

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DOES YOUR NMN SUPPLEMENT HAVE GMP ON THE BOTTLE? OURS DOES
AND, HERE IS WHY IT IS IMPORTANT. Many supplements claim that their product is
manufactured in a GMP facility but is it displayed on the bottle? If not, it
is because the manufacturer will not allow the claim to be made if they are
NOT a GMP facility. All Genex Formulas products are manufactured in a GMP
certified facility and we proudly display this on our labeling. This is
extremely important since GMP (which stands for ‘Good Manufacturing Practices)
are a set of best practices for dietary supplement manufacturing in the United
States. Establish, maintained, and updated by the U.S. FDA, these regulations
establish the baseline requirements for dietary supplement companies and
manufacturers looking to produce dietary supplement products. Covering
everything from labeling and packaging to ingredient sourcing and formulation
– GMPs have been put in place for each step of the dietary supplement
manufacturing process. Along with acting as a quality control and assurance
measure, GMPs requirements help ensure that dietary supplement products
consistently meet specifications for purity, strength, and composition. GMPs
are overseen and enforced by a number of well-established and credentialed
third party auditors, like NSF. WHAT IS NMN? NMN is an entirely natural
compound found in our bodies. Various food sources also contain this compound
in minuscule amounts. Edamame which has one of the higher contents, only show
less than 1.9mg/100g. NMN is a direct and potent NAD+ supplement. Mice given
an oral supplement of NMN showed increased liver NAD+ levels in just 10
minutes and showed an increase in muscle tissue by 30 minutes. Increased NAD+
levels stimulate energy DNA repair and SIRTUIN activity. SIRTUINS are the
longevity-genes shown to be active during caloric restriction and life-
extension in many animal models. NAD+ helps to breakdown food like sugars into
energy. Promotes Healthy Cardiovascular Function. DNA Repair – NAD+ is used to
repair broken DNA strands. SIRTUIN Activator – NAD+ is required for our
longevity genes to work. NMN is THE compound used by Harvard Scientists to
reverse some signs of aging tissue in mice that started the rush to NAD
supplements. THE SCIENCE Scientists have now confirmed a direct link between
falling NAD+ levels and aging in both animals and human subjects. A
breakthrough study published by Harvard scientists in 2013 showed for the
first time that some aspects of aging might be reversible. After treating old
mice with NMN, several biometric markers that were subsequently measured
resembled those of young mice: “the human equivalent of a 60-year old with
markers resembling that of a 20-year old”. The research and understanding into
NAD+ metabolomics are ongoing, but what the science has highlighted thus far,
is the importance of supporting and maintaining our NAD+ levels.A long-term
evaluation of oral supplementation of NMN in mice was found to be effective at
improving NAD+ levels safely. Mice supplemented with NMN vs. a control group
showed notable age-associated differences in mass, energy, blood sugar, lipid,
gene expression changes, mitochondrial oxygen use, eye function, bone density
and immune function with no apparent toxic effects. These statements have not
been evaluated by the FDA. This product is not intended to diagnose, treat,
cure or prevent and diseases. Is there a correlation between falling NAD
levels and aging? Scientists have discovered that as we get older, our NAD+
levels steadily decrease, and by the time we get to our late 70s &80s, our
NAD+ levels appear to be much lower, than those of younger people. The science
is starting to clearly show a definite correlation between falling NAD levels
and an age-related decline in health & wellness. In 2013 Harvard researchers
published a study, where they were able to reverse some parts of aging by
treating old mice with NMN, a direct NAD+ precursor supplement. After ten days
of treatment, key biometrics markers measured resembled those of much younger
mice. For the first time, we have real evidence that some aspects of aging may
be reversible. In 2017 the same team published a follow-up article. It
demonstrated a new understanding of how NAD+ is not only used to repair
damaged DNA but how it also stimulates the repair process. It does this by
blocking another protein called DBC1 that interferes with the PARP-1 DNA
Repair enzyme. Read more New NMN Transporter Slc12a8 Found How NMN is taken up
into cells has not been entirely clear. However, a recent study has identified
that Slc12a8 is highly expressed and regulated by NAD+ in the small intestine.
When NAD+ levels are low, the cells respond by turning on more Slc12a8
transporters. It has been further shown that Slc12a8 specifically transports
NMN and not NR. The study demonstrates that Slc12a8 has a critical role in
regulating intestinal and systemic NAD+ supply. Read more The Power of Three!
Why NMN, Resveratrol & Berberine is a Powerful Combination So far, at least
three major longevity pathways have been identified by researchers. The
SIRTUIN gene regulators that silence genes and repair DNA, the AMPK activated
pathway, and the mTOR pathway which influences cell division and growth. The
power of three, positively promote these synergistic pathways to better our
chances of a favorable outcome when supplemented together. NMN is excellent,
as it provides the fuel for Sirtuins and the substrate for DNA repair.
However, Resveratrol is also very important as it independently activates
Sirtuins and to a lesser extent, inhibits mTOR activity. Finally, Berberine
which is one of the better studied natural plant extracts is a good AMPK
activator that stimulates mitochondrial biogenesis and offers other benefits
by turning on genes similar to those turned on by exercise. Read more NMN
Nicotinamide Mononucleotide NAD+ Booster NMN is an entirely natural compound
found in our bodies. Various food sources also contain this compound in
minuscule amounts. Edamame which has one of the higher contents, only show
less than 1.9mg/100g. NMN is a direct and potent NAD+ supplement. Mice given
an oral supplement of NMN showed increased liver NAD+ levels in just 10
minutes and showed an increase in muscle tissue by 30 minutes. Increased NAD+
levels stimulate energy, DNA repair, and SIRTUIN activity. SIRTUINS are the
longevity-genes shown to be active during caloric restriction and life-
extension in many animal models. Resveratrol with BioPerine At Genex, we chose
to use an all-natural and organic source of Resveratrol that was extracted
from Japanese knotweed (also known as Polygonum cuspidatum root) which
contains 50% Trans-Resveratrol. Resveratrol has several remarkable properties
that help to support good health. Most commonly, Resveratrol is known as the
longevity supplement found in red wine and generally as an effective
antioxidant. Resveratrol is also the most potent naturally occurring direct
SIRTUIN activating compound. Berberine AMPK Activator AMPK Activator Berberine
is a natural plant-based compound found in several different plants, including
Barberry (Berberis vulgaris). Berberine is known as a direct AMPK activator.
The AMPK pathway, in short, is one of the things that happens during exercise,
the expression of a set of genes known to promote longevity. Both human and
animal studies show Berberine may have the potential to support healthy blood
sugar levels, already in the normal range. Berberine may also help support
healthy cholesterol, gut, brain, heart, and inflammation. Berberine is a
general health and wellness supplement that has been used as a traditional
herb for thousands of years. Read more NMN Nicotinamide Mononucleotide NAD+
Booster Resveratrol with BioPerine Extra Strength Berberine AMPK Activator NMN
500mg Dose Sirtuin Activator – Longevity Support ✓ ✓ ✓ Blood Sugar Support ✓
Antioxodent ✓ ✓ ✓ ✓ Promotes Healthy Immune Funtion ✓ ✓ ✓ ✓ AMPK Activator ✓ ✓
GMO Free ✓ ✓ ✓ ✓ Glutten Free ✓ ✓ ✓ ✓

Features:

  • There are many cheaper alternative sources to buy NMN today, but are you getting what you paid for? If the price for NMN is too good to be true, it probably is not NMN. We use pharmaceutical grade NMN in our product, so make sure you get what you pay for!
  • FULLY STABILIZED – Our NMN comes in a completely shelf-stable non-refrigerated form. We use opaque jars and desiccant packs to protect it from light and moisture to ensure it maintains maximum potency.
  • Certified 99% Pure NMN – Direct NAD+ Precursor Supplement SIRTUIN Activator – NAD+ is required for our longevity genes to work.
  • Dr. Sinclair's Recent trials show Old Mice treated with NMN restored blood vessel capillary density.
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